OrganRXTM Tissue builds quality, transplantable tissue for organ repair needs. Using the advanced biomimetic OrganRXTM technologies allows for the construction of functional organ tissue for therapeutic discoveries.
Biopico’s innovation involves the development of endothelium-epithelium interface using Laplace fluidic-stop channels and fluidic programming using gravity-driven unidirectional recirculation of media. This enables layering of extracellular matrix gel and tissues without using artificial membranes, allowing co-culture of endothelium with epithelium and the free migration of immune cells through the extracellular matrix gel. Further, multidimensional tilting of the OrganRX plate produces periodic recirculation with programmable resident times across organs that are connected in series and parallel. The system can also integrate multiple individual organs or organoids developed in traditional culture protocols into the OrganRX plate.
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