Author: admin@bio
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Angiogenesis
To study vessel sprouting, remodeling, drug responses, transplantation, and regenerative therapies.
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Vasculogenesis
To study vessel maturation, immune trafficking, drug delivery, and cross-organ communication.
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Society of Toxicology 62nd Annual Meeting and ToxExpo
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Society of Neuroscience Annual Meeting, San Diego (2022)
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Three-Dimensional Multi-organ Culture Systems for Toxicological Analysis In Vitro
Webinar Summary : The multi-organ chip allows for the simultaneous culture of multiple organs, each grown from one or more interacting cell types. The continuous fluid flow provided by the microfluidic model also emulates the physiological flow of nutrients, metabolites, drug compounds, toxins, and other molecules from organ to organ. The culture conditions of the…
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OrganRX™ CRO Services
TUMOR MICROENVIRONMENT FOR THERAPEUTIC SCREENING Using the OrganRX™ Plate and OrganRX™ System, cell-cell and cell-matrix interactions within 3D tumor spheroid models are studied to provide deeper insights into drug response and tumor behavior. The OrganRX™ Plate supports co-culture of tumor spheroids/organoids with stromal, endothelial, and immune cells and can model multiple replicates of multi-organ interactions…
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OrganRX™ Plate & Kits
The organ plate is an injection molded glass bottom disposable plate. Currently the plate has six multi-organ units. The OrganRX™ plate can accommodate multiple micro-organs such as liver, gut, kidney and brain. The plate is activated to passive gravity-driven unidirectional shear flow to culture multi-organs. OrganRX™ Plate The OrganRX™ plate is injection-molded disposable plate with a glass bottom.…
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OrganRX™ System
The multi-organ recirculation system (OrganRX™) provides passive gravity-driven unidirectional shear flow to multi-organ cultures. Biopico System offers a range of options for individual analysis and high-throughput screening. OrganRX™ Single-Plate System Our OrganRX™ System provides recirculation of media across multiple organs with a specified fluidic shear stress for the recapitulation of organs. The OrganRX™ system is made up…
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OrganRX™ Tissue Plate
The OrganRX™ Tissue plates are pre-seeded with cells in 3D gel as ready-to-use tools that make reproducible micro vessel biology simple and efficient. The standardized seeding and controlled flow conditions will help to achieve more reproducible results with less setup time. Key Advantages to using the OrganRX™ Plate: Ready on arrival: Cold-shipped and assay-ready. Imaging made…
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Importance of Fluidic Shear Stress using OrganRXTM System
Within the human body, fluids, cells, and particles are in constant motion, flowing from one area to another. In such an environment, everything is dynamic and ever-changing. Replicating the motion of biological fluid in an OrganRXTM system is essential to understand how drugs will function when applied in real life. That specific quality is typically lost…